This 2007 action-adventure beat 'em up, inspired by early Spider-Man films, features a core loop where you fight villains globally, then convert them into co-op sidekicks for future missions. The game blends platforming with hack-and-slash combat, offering a humorous reinterpretation of cinematic moments and supporting local two-player co-op across locations like Tokyo and Egypt. Note: This title was removed from digital storefronts in 2014.
The gameplay loop centers on traversing various global locations—including settings like Tokyo, Egypt, and Nepal—while engaging in fast-paced combat scenarios. As the main hero, players utilize signature abilities to overcome waves of enemies and challenging boss encounters. This title falls under the genres of Platform, Hack and slash/Beat 'em up, and Adventure.
A defining feature of this title is the mechanic of recruiting defeated foes. After successfully besting a major antagonist in an epic confrontation, that character joins the player's roster, offering new abilities or support during subsequent missions. This system encourages experimentation with different character combinations throughout the adventure.
The game offers a distinct take on the established lore by incorporating a humorous interpretation of major on-screen moments from the films. Furthermore, it features a dedicated co-op multiplayer mode, allowing a second player to join the action either as the primary hero or as one of the newly recruited sidekicks, facilitating cooperative exploration and combat across the globe.
Players engage in beat 'em up action combined with platforming challenges. The core objective involves progressing through levels, defeating enemies, and utilizing the unique powers of recruited villains to advance the story.
It is important to note that this main release, originally published by Activision, was de-listed and removed from digital storefronts on January 1, 2014. Therefore, current access is generally limited to physical copies or older digital licenses.
This main release does not feature any downloadable content (DLC) or official expansions.
This title was released on the Xbox 360 and Microsoft Windows platforms.

Defeat Spider-Man’s most famous enemies, like Venom, Green Goblin, and Doc Ock to add them to your epic array of playable sidekicks in this movie trilogy inspired adventure. Experience ground-breaking Co-operative Multiplayer, as Spider-Man or a sidekick, in exotic spots around the globe, including Tokyo, Egypt and Nepal. Inspired by the Spider-Man movies, this Action Adventure game reinterprets big-screen moments and battles with a humorous twist. Replay chapters with different sidekicks and eventually with Black-Suited Spider-Man.

DS version of Spider-Man: Friend or Foe. In this game, the player can use two characters in 3D levels from a roster of both heroes and villains.
