This 2007 main installment is a platform adventure where you explore levels to stop Doctor Cortex from creating a Titan army using the substance Mojo. The core gameplay introduces fighting combos, allowing you to use punches and kicks against enemies. A distinctive feature is the ability to "jack" defeated Titans to control them. Collecting Mojo rewards you with new moves or ability upgrades, directly tying combat progression to exploration across platforms available on Wii, PS2, Xbox 360, and PSP.
The gameplay loop blends traditional platforming exploration with a significant emphasis on close-quarters combat. For the first time in the series, players utilize a dedicated fighting system featuring punches, kicks, and various combat combos to engage enemies directly.
A central and unique feature of this adventure is the ability to "jack" defeated enemies. By overpowering specific foes, the player can temporarily take control of these mutated creatures, utilizing their unique strengths and abilities to overcome obstacles or destroy larger threats within the game world.
As players defeat enemies or destroy environmental objects, they release the vital substance, Mojo. Collecting sufficient amounts of this substance is directly tied to character progression. Accumulating enough Mojo rewards the player with either new combat moves to expand their fighting repertoire or permanent ability upgrades necessary for accessing previously unreachable areas.
This main installment in the series was made available on the Xbox 360, PlayStation 2, PlayStation Portable, and Wii consoles.
No, this game does not feature any downloadable content (DLCs) or expansions, meaning the experience is entirely contained within the base release.
The integration of the Mojo collection system directly into combat upgrades, coupled with the strategic necessity of the "jacking" mechanic to control powerful enemies, sets this entry apart from standard platforming experiences.

The Game Boy Advance version of Crash of the Titans features linear 2D gameplay where the focus is to break crates while jacking Titans, it also has its own story merging the DS and console versions.

The Nintendo DS version of Crash of the Titans is a platform game with beat 'em up elements, it differs from the console version in its plot and extensive use of the touchscreen and microphone.

Crash of the Titans is a 2D side-scroller beat 'em up game released on October 2007 and developed by DeValley. It is one of the three portable versions of Crash of the Titans, along with the Nintendo DS and Game Boy Advance versions.