《The Binding of Isaac》是一款于2011年发行的、带有浓厚Rogue-like元素的随机生成动作RPG射击游戏。玩家扮演小男孩以撒,逃入充满怪物的地下室,通过不断向下探索、战斗和收集奇异宝物来改变自身形态和能力。其核心玩法是永久死亡机制下的重复游玩,每次闯关的地图、敌人和道具组合都完全随机,极大地增加了重玩价值。游戏剧情基于《圣经》故事改编,氛围黑暗,拥有多达十余种不同的结局。该作已推出官方可下载内容(DLC)并有重制版本,社区反馈集中于其海量道具的协同效应和深度探索性。
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The Binding of Isaac: Rebirth is a top down, procedurally-generated roguelike game, remade based on the original game The Binding of Isaac. You play as Isaac, a little boy who is chased to the basement by his mother who intends to kill Isaac for her savior. You explore different levels, collect items and try to defeat your mother.. and whatever other evil awaits you. If you die, you restart with none of your items you collected, and you must explore the basement and beyond again.

The Binding of Isaac: Wrath of the Lamb is an official DLC expansion to The Binding of Isaac, which adds new Items, Rooms, Enemies, Bosses, and more.