The Binding of Isaac je naslov iz 2011. godine, akcijski RPG s elementima \"roguelike\" shootera gdje, bježeći od majke, spuštate se kroz nasumično generirani podrum. Ključno je preživljavanje, borba protiv grotesknih stvorenja i skupljanje stotina bizarnih predmeta koji drastično mijenjaju vaš izgled i sposobnosti, osiguravajući visoku ponovljivost. Priča je labavo bazirana na biblijskoj priči, a igra je poznata po mračnoj atmosferi i brojnim mogućim završecima.
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The Binding of Isaac: Rebirth is a top down, procedurally-generated roguelike game, remade based on the original game The Binding of Isaac. You play as Isaac, a little boy who is chased to the basement by his mother who intends to kill Isaac for her savior. You explore different levels, collect items and try to defeat your mother.. and whatever other evil awaits you. If you die, you restart with none of your items you collected, and you must explore the basement and beyond again.

The Binding of Isaac: Wrath of the Lamb is an official DLC expansion to The Binding of Isaac, which adds new Items, Rooms, Enemies, Bosses, and more.